Targeting Chromatin Remodeling for Cancer Therapy
نویسندگان
چکیده
منابع مشابه
DNA looping-dependent targeting of a chromatin remodeling factor
Eukaryotic genomes are highly complex structures that must be efficiently packaged into relatively small nuclei in order to accommodate multiple DNA-dependent processes, from transcription and DNA replication to DNA repair and recombination. The compaction of genomes is hierarchically achieved at two distinct levels: (1) the compaction of DNA into nucleosome arrays and (2) the three-dimensional...
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ژورنال
عنوان ژورنال: Current Molecular Pharmacology
سال: 2019
ISSN: 1874-4672
DOI: 10.2174/1874467212666190215112915